FDA-Approved GLP-1 Injection
FDA-approved, once a week. FDA-approved GLP-1 injections for chronic weight management, used once a week. If your provider prescribes one, they send it to the maker’s own pharmacy, LillyDirect or NovoCare Pharmacy, where you pay their cash price directly, or to your own pharmacy to use insurance. StackRx charges for your visits; we don’t fill or sell these medicines.
- FDA-approved for chronic weight management in adults
- Once a week, at home
- Dose set and adjusted by your provider
- Filled by a licensed pharmacy
Weekly injection · $65 visit · medicine from $199/mo, paid to the pharmacy. Prices are preliminary.
How it works
- Answer the evaluation: your health and family history, your weight and goals, and every medicine and supplement you take.
- Get lab work if your provider asks for it.
- If your provider prescribes it, they send it to LillyDirect or NovoCare Pharmacy, which bills you directly and ships it to you, or to your own pharmacy to use your insurance.
- Inject once a week, on the same day each week. Doses start low and go up slowly; your provider sets the pace.
- What’s in it
- An FDA-approved GLP-1 medication; your provider decides which
- Form
- A weekly injection under the skin, from a prefilled pen or a vial, depending on the medication
- Who it’s for
- Adults with a BMI of 30 or more, or 27 or more with a weight-related condition such as high blood pressure or type 2 diabetes
- Labs
- If your provider asks: blood work before you start
- Cost
- Visits: $65 to start, then $45 for each follow-up or dose change. Medicine is paid to LillyDirect, NovoCare Pharmacy or your pharmacy.
Your options, and what they cost.
- Zepbound (tirzepatide) (From $299 a month): Weekly single-dose vials or a multi-dose KwikPen from LillyDirect: $299 a month at 2.5 mg, $399 at 5 mg, and $449 at 7.5 to 15 mg if you refill within 45 days ($499 to $699 if you don’t). Paid to LillyDirect.
- Wegovy (semaglutide) pen (From $199 a month): Weekly pens from NovoCare Pharmacy: $199 a month for the first two months (0.25 and 0.5 mg, through December 31, 2026), then $349 a month at any dose up to 2.4 mg, or $399 for the 7.2 mg Wegovy HD pen. Paid to NovoCare Pharmacy.
- With insurance (Your plan’s price): Your provider can send the prescription to your own pharmacy instead, which checks what your insurance covers.
What to expect
- First weeks
- A low starting dose, to help your body adjust. Nausea and other stomach side effects are most common early on.
- The next few months
- Your provider raises your dose step by step, if you’re tolerating it, and checks in along the way.
- Ongoing
- Your provider reviews how it’s going and adjusts your plan. Everyone responds differently.
Important safety information
Before you start
Your provider reviews your health history, medicines and allergies before prescribing, and prescribes only if it’s right for you. Tell your care team about any side effect, and get emergency care for chest pain, trouble breathing, or swelling of the face, lips or throat.
Common side effects of GLP-1 medications
Nausea, diarrhea, vomiting, constipation, stomach pain, indigestion, headache and tiredness are the most common, usually early on and as the dose goes up. They often ease with time. Tell your provider if they don’t.
Important safety information for GLP-1 medications
GLP-1 medications for weight carry a boxed warning: in studies in rodents, they caused thyroid C-cell tumors. It isn’t known whether they cause these tumors, including medullary thyroid cancer, in people. Don’t take them if you or a family member has had medullary thyroid cancer, or if you have multiple endocrine neoplasia syndrome type 2 (MEN 2). Tell your provider right away about a lump or swelling in your neck, trouble swallowing, a hoarse voice or shortness of breath. They can also cause inflammation of the pancreas (pancreatitis), gallbladder problems, low blood sugar (especially with insulin or a sulfonylurea), kidney problems from dehydration, and serious allergic reactions. They aren’t used during pregnancy. Get emergency care for severe stomach pain that doesn’t go away, with or without vomiting.
FDA status
This is an FDA-approved medication: the FDA has reviewed it for safety and effectiveness for chronic weight management in adults, alongside diet and activity.
About FDA-Approved GLP-1 Injection
Which one will I get?
Your provider decides with you, based on your health, your history and what you prefer, and only if one is right for you.
Can StackRx fill it?
No. These medicines come from the makers’ own pharmacies, LillyDirect and NovoCare Pharmacy, or from your own pharmacy if you use insurance. We charge for your visits only.
What does it cost?
Visits: $65 to start, then $45 for each follow-up or dose change. The medicine is paid to the pharmacy: from LillyDirect, Zepbound is $299 to $449 a month; from NovoCare Pharmacy, the Wegovy pen is $199 a month for the first two months, then $349. With insurance, your plan’s price.
Are you affiliated with Eli Lilly or Novo Nordisk?
StackRx isn’t affiliated with Eli Lilly or Novo Nordisk. LillyDirect and NovoCare Pharmacy are their own pharmacies: they set these prices, bill you directly and can change them at any time. Prices as of October 2026. Zepbound, KwikPen, LillyDirect and Foundayo are trademarks of Eli Lilly and Company; Wegovy and NovoCare are trademarks of Novo Nordisk.
Injection or tablet?
Both are options. Your provider can talk you through the differences, including how each is taken.